Baker, P.A., Meyer, M.D., Tsang, A. and Uribe, R.A. (2019). Immunohistochemical and ultrastructural analysis of the maturing larval zebrafish enteric nervous system reveals the formation of a neuropil pattern. Scientific Reports, Volume 9, Article number: 6941 www.nature.com/articles/s41598-019-43497-9
In this paper, we describe that the zebrafish intestinal wall contains a meshwork of neural tissue, called the myenteric plexus, which matures between 7 and 18 days post fertilization.
Hutchins, E.J., Kunttas, E., Piacentino, M.L., Howard IV, A.G.A., Bronner, M.E. and Uribe, R.A. (2018). Migration and diversification of the vagal neural crest. Developmental Biology, Invited Review article in the Special Edition celebrating the 150th Anniversary of the discovery of Neural Crest doi.org/10.1016/j.ydbio.2018.07.004 PMID: 29981692
In this paper, we summarize current knowledge of vagal neural crest development across vertebrates.
Rajan SG, Gallik KL, Monaghan JR, Uribe RA, Bronner ME, Saxena A. (2018). Tracking neural crest cell cycle progression in vivo. Genesis. e23214. In the Special Anniversary Edition celebrating 150 years of Neural Crest Research doi.org/ 10.1002/dvg.23214 PMID: 29956448
In this paper, we collaborated with the Saxena lab to create a novel cell cycle occupancy reporter, in neural crest cells.
Uribe, R.A.*, Hong, S.S. and Bronner, M.E. (2018). Retinoic Acid temporally orchestrates colonization of the gut by vagal neural crest cells. Developmental Biology, Jan 1;433(1):17-32. PMID: 29108781 10.1016/j.ydbio.2017.10.021*corresponding author
In this study, it was discovered that a very fine window of time is critical for Retinoic Acid to affect vagal neural crest invasion into gut tissue. We also discovered that the transcription factor Meis3 is functionally important downstream of Retinoic Acid, expanding our knowledge of this critical Gene-Environment interaction during development.