Welcome to the Laboratory of Neural Crest and Enteric Nervous System Development
We study how genetic, cellular and environmental factors contribute to and influence stem cell and nervous system development in vivo. Our mission is to use a systems-level approach to enhance understanding of fundamental mechanisms that orchestrate stem cell transformation into specialized cells and tissues. Our approach integrates and leverages zebrafish organismal-level, tissue-level and cellular-level developmental biology, synthetic & recombinant gene expression paradigms, single-cell omics, in vivo high resolution microscopy and computational methods.
Our ultimate goal is to increase foundational knowledge to help build better therapies and cures for neurodevelopmental defects and cancer.