We study how genetic, cellular and environmental factors contribute to and influence stem cell and nervous system development. •Our mission is to use a systems-level approach to enhance understanding of fundamental mechanisms that orchestrate stem cell transformation into specialized cells. Our ultimate goal is to help build better therapies and cures for neurodevelopmental defects and cancer. To this end, we will collaborate with local researchers and share results and reagents in a collegial manner. •The Uribe lab strives to disseminate our scientific findings to the scientific and non-scientific communities and to train the next generation of scientists.